Parveen Azim, Muhammad Mumtaz Khan, Naveed Sharif, Ehsan Gul Khattak

84 – 88

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OBJECTIVE: The aim of our study is to determine the frequency of various types of abnormal uterine bleeding in our set up and to analyze their findings on endometrial biopsy.

DESIGN: It is an observational simple descriptive type of study.

METHODS: The endometrial biopsy reports of 128 patients admitted for abnormal uterine bleeding in the Department of Obstetrics and Gynecology in Khyber Teaching Hospital, Peshawar from 1st January 2008 to 31st December 2010 were analyzed.

RESULTS: The most frequent clinical feature was polymenorrhagia (35%) gestational bleeding (27%), menorrhagia (18%), metrorrhagia (9%) and postmenopausal bleeding (6%). The endometrium morphology was normal in polymenorrhagia (19%), menorrhagia (9%) and metrorrhagia (5%) cases. Endometrial pathology was detected in (66) % cases. The most common causes of AUB in our study on endometrial biopsy were related to gestation (23%) and spectrum of histological findings pointing at some hormonal disorder (21%). The frequency of endometrial malignancy was remarkable i.e., 07%. Other significant pathologies included chronic endometritis 10%, polyps 10%.

CONCLUSION: The most common presenting complaint of abnormal uterine bleeding was

polymenorrhagia. In young women the underlying pathology of AUB gives a clue to some hormonal disorder or to some gestational pathology. In perimenopausal and postmenopausal women it strongly points at malignancy.

KEY WORDS: Abnormal uterine bleeding, polymenorrhagia, endometrial biopsy