Gul Zaman Khan Niazi, Fahar Adnan, Syed Naseem Bukhari,Mahmood-ul-Hassan Taga, Muhammad Zubair Zaffar, Hafiz Abdul Kabir

250-254

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  ABSTRACT

Objective: To assess the relationship between hs-CRP (high sensitivity C-reactive protein) and acute ST-elevation myocardial infarction (STEMI), and the association of hs-CRP with common coronary disease risk factors and angiographically important coronary artery disease.

Study Design: A cross-sectional analytical study.

Place and Duration: From 3^rd Mar 2020 to 3^rd Aug 2020 at the Department of Cardiology in Ch. Pervaiz Elahi Institute of Cardiology Multan.

Methodology: A total of 150 patients diagnosed with STEMI were included in the study after passing through selection criteria. All the participants were evaluated for hypertension, diabetes, and smoking status. Blood samples were collected to analyze hs-CRP values following a protocol. Based on angiographic findings patients were divided into three groups: mild, moderated, and severe coronary artery disease.

Results: The result found out significant relation between mean hs-CRP values and hypertension, diabetes, dyslipidemia, and Killip class (p<0.05). Although, the values of mean hs-CRP for double and triple coronary vascular diseases were higher than the single vascular disease (SVD, 0.62 mg/dl; DVD, 0.71 mg/dl and TVD, 0.87 mg/ml), no significant difference can be found in terms of a number of vessels involved. It was found out that mean hs-CRP values for three groups based on Syntax score are directly related to syntax scores. (Syntax score ≤22, 0.62 mg/ml; Syntax scores >22–32, 0.79 mg/ml and syntax score >32, 1.91 mg/dl), however, the difference remained insignificant.   

Conclusion: The study has found hs-CRP as a potential candidate for navigating the development of ST-elevation myocardial infarction and predicting its prognosis.

Keywords:  Coronary artery disease, Myocardial infarction, Clinical findings, Angiographic findings, Inflammatory markers, hs-CRP, Clinical correlation.

How to Cite This:

Niazi GZK, Adnan F, Bukhari SN, Taga MH, Zaffar MZ, Kabir HA. An assessment of angiographic and Clinical correlation among high-sensitivity C-reactive protein with acute ST-elevation myocardial infraction. Isra Med J. 2021; 13(4): 250-254.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.