MUHAMMAD JAWAD ANWAR, MUHAMMAD LUTFULLAH, SAJEELA HAMEED

262-266

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ABSTRACT

OBJECTIVE: To measure and compare the glucose and Insulin levels of asymptomatic offspring of type 2 diabetic patients with asymptomatic offspring of non diabetics.

STUDY DESIGN: Case control study.

PLACE AND DURATION: Department of Pathology PGMI, Lahore and Diagnostic Laboratory of UVAS, Lahore, from 1st October 2009 to 30th June 2010.

METHODOLOGY: Non diabetic healthy offspring of diagnosed patients with type 2 diabetes mellitus attending the medical departments of LGH Lahore, both male and female below 30 years of age, documented by normal fasting blood glucose level and not having any symptom of diabetes were included.

RESULTS: In this study glucose and insulin were measured in 100 subjects. Glucose was measured by GOD PAP method and Insulin by ELISA technique. Mean ± SD of glucose in control group was 80.75±14.21and in study group was 80.92±13.38having non significant difference having P value 0.081. Mean±SD of insulin in control group was 16.80± 4.09 and in study group was 18.40±13.32 having non significant difference having P value 0.098.

CONCLUSION: Insulin and glucose concentrations were within normal limits, and were not having any significant direct or inverse relationship (p=0.076).

 

KEY WORDS: Glucose oxidase paraaminophenazone (GOD PAP), Enzyme linked immunosorbent assay (ELISA), Type 2 diabetes mellitus (T2DM), Insulin, Glucose.