Title:
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Pregnancy in Wilson’s disease – Compliance is a Must
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Authors:
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Published on:
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2017-08-31
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Journal Reference:
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Volume 9- Issue 4 July - August 2017
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Pages:
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266-268
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Download Abstract:
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DOI:
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ABSTRACT
Wilson's disease is a genetic disorder, related to the defective copper metabolism. Accumulation of excessive copper in different body organs especially liver and brain results in clinical manifestation. Typical to this disease is asymptomatic period. It may progress to acute liver failure in case of noncompliance to treatment or in the presence of other risk factors. In the past, patient with Wilson's disease in reproductive age suffers from sub fertility and miscarriages due to excessive accumulation of copper. Chelator therapy in recent past revolutionized the treatment of Wilson's disease giving hope to the pregnant couples. Continuation of chelator therapy is recommended throughout the pregnancy with multidisciplinary approach to achieve the good maternal and fetal outcome.
KEY WORDS: Wilson's disease, Acute liver failure, Chelator therapy, Liver transplant.
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